Zebra ZD421-C ribbon cartridge's desktop printer

Zebra ZD421-C
4-inch Desktop Printers

The Zebra ZD421-C ribbon cartridge Desktop Printer incorporates features that position it as the most user-friendly printer in its class. The ZD421-C features a dedicated cartridge for swift, effortless, and error-proof ribbon loading.

Equipped with the Print DNA suite of software and achieves a print speed of 6 inches (152 mm) per second at 203 dpi, ensuring efficient and high-quality printing capabilities.

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The ZD421 keeps it simple with a 3-button interface and 5 clear status icons for easy user interaction.


Features a Real-Time Clock (RTC) and seamless integration with the Link-OS operating system, ensuring precise timekeeping and efficient communication for enhanced performance.


Zebra’s ZD421 features a standard USB and USB Host, with optional Ethernet, Serial, and Bluetooth® 4.1.


The ZD421 makes media loading easy with its dual-wall frame and user-friendly OpenACCESS™ design, ensuring a sturdy and smooth operation.

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Zebra ZD421-C Photo Gallery

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Multi-functional Mobile Solutions

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The dual-wall frame construction of the ZD421-C ensures enhanced durability and stability for reliable performance in diverse printing environments.

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Equipped with full-width, adjustable reflective/black mark sensors and multi-position transmissive/gap sensors, the ZD421-C ensures accurate media detection and versatility for various printing needs.

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The ZD421 prints quickly at 6 inches per second (203 dpi) and 4 inches per second (300 dpi), offering high-resolution output to meet different needs.

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Field Service

With a Real-Time Clock (RTC) ensuring precise timekeeping, the ZD421 supports versatile print methods, including both Thermal Transfer and Direct Thermal, providing flexibility for various printing needs.

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The ZD421 is a special thermal printer with a ribbon cartridge that loads quickly and easily every time. Plus, a smart chip tells you when it’s time to replace the ribbon.

Power + Resilience

Optimize your workflow with the Zebra ZD421-C.

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